Weboxidative stress can damage cells, proteins and dna and can eventually lead to varied chronic diseases such as cancer, diabetes, cardiovascular disease,. Webthis article provides an overview of current evidence regarding the relationships between working time arrangements and various social and family. Webphysically, shift work can disrupt circadian rhythms, which has deleterious effects on sleep. Guided by the stress process model (spm), this study examines the association. Webthis study aims to elucidate the negative relationship between night and day shift work schedules and the quality of life among nigerian health workers.