An absolutemonocyte count above 10%, or 800 per mm3, is considered high. It’s called monocytosis and might mean your body is responding to something. This is because having a highabsolutemonocyte count could mean there’s a deeper issue. Read on to learn more about your monocyte count and why it’s so important to your health. Absolutemonocyte count. The total number of monocytes per liter of blood.Does a highmonocyte count mean I have cancer? Causes of HighMonocytes. A highmonocyte count, or monocytosis, generally indicates the immune system is activated. Highmonocyte percentage with normal absolute count: Can indicate relative monocytosis due to decreases in other white cells rather than true monocyte increase. AbsoluteMonocyte Count Test. Gain vital insights about your immune and blood health to diagnose various conditions associated with abnormal monocyte levels. A highabsolutemonocyte count means when the monocyte count is more than 2%-8% of the total WBC count. This can be determined with the AbsoluteMonocyte Count test. on my cbc test my monocytes was normal but my monocytesabsolute was high. why is that? had mono a month earlier broke out in rash etc from penicillin: Wouldn't be odd... Highabsolutemonocyte count. The body may make more monocytes once an infection is detected or if the body has an autoimmune disease. The site owner hides the web page description.